Figure 1: Average distance ran over three days of testing for BL10 (n=7) versus MDX (n=9) male mice at 14 weeks. Mean with a standard error showing statistical significance (***) with a p-value of <0.001
In the exhaustion assay, mice are subjected to a forced running paradigm that measures their time to fatigue. Treadmill speed is increased incrementally until the point when a mouse reaches exhaustion. The total distance ran during the exhaustion period is measured, as well as the distance run normalized to the animal’s body weight.