Pre-clinical Positioning

AGADA performs efficacy testing in mouse models of human disease.

Efficacy testing in mouse models is a key ‘de-risking’ step in drug development, particularly for rare genetic diseases (orphan drug development).

AGADA aids in the development, design, and execution of robust efficacy studies including:
  • Functional outcomes
  • Biomarker outcomes
  • Histology
  • Dissection and sample processing
Studies are done under strict QA/QC environment including extensive training of staff on protocols and procedures.

Pre-clinical efficacy studies are increasingly required by regulators to show a ‘proof of concept’ for granting of orphan drug status. AGADA has provided many of these regulatory-ready studies.

With hundreds of efficacy studies in many mouse models of neuromuscular disease, AGADA brings a wealth of experience to carryout your efficacy studies in mouse models